Gene expression is the process of reading genetic information and building proteins and RNA molecules for the cell to function. The primary tool to understand global - or whole genome - expression of genes are DNA microarrays. Microarrays
are tools to understand the genetic active state, or transcriptom,
of an organism. The 'transcriptom' reflects the genetic underpinnings
of an actual physiological or cellular process at any given moment
in the life of an organism or cell. Microarrays are also used to
test genotype and polymorphism of genomes of individuals (in the
case of human genetics) or strains of infectious microorganisms.
As such, microarrays are novel diagnostic tools to test the genetic
conditions of individuals rather than populations.
Here at SciScript
we have extensive experience with the genotyping of viral genomes
and analysis the transcriptom of various animal cell lines used
to study cancer and immunology. This work is based on collaboration
with researchers at The Scripps Research Institute in La Jolla,